OpenProtect

Homepage: http://opencompt.com/
Supports: ClamAV via MailScanner
OpenProtect is a server side e-mail protection solution consisting of MailScanner, Spamassassin, ClamAV with support for Sendmail, Postfix, Exim and qmail. It also consists of a fully automatic installer and uninstaller, which configures everything automatically including setting up perl modules and virus scanner settings.